Traditional Chinese medicine component structure analysis and optimization method using comprehensive evaluation model and application

The invention provides a traditional Chinese medicine component structure analysis and optimization method utilizing a comprehensive evaluation model and application. The method comprises the following steps: separating or preparing traditional Chinese medicine potential active components; establish...

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Hauptverfasser:	FENG LIANG, ZENG JINGQI, MAO YUZHI, JIA XIAOBIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a traditional Chinese medicine component structure analysis and optimization method utilizing a comprehensive evaluation model and application. The method comprises the following steps: separating or preparing traditional Chinese medicine potential active components; establishing a target pharmacodynamic activity evaluation model, and obtaining a plurality of pharmacodynamic evaluation index results of the potential active components; calculating contribution degrees of different potential active components to target pharmacodynamic activity by utilizing a comprehensive evaluation model; the component with the highest target pharmacodynamic activity contribution degree is selected, and analysis and optimization of the traditional Chinese medicine component structure are achieved. Compared with a traditional Chinese medicine substance basic analysis method, the method is scientific, rigorous, simple, clear, reliable in result and high in operability, multi-index comprehensive evaluation