Bifunctional degradation agent and use method thereof

Described herein are bifunctional degradation agent compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins. 本文描述了双官能团降解剂化合物、它们的各种靶标、它们的制备、包含它们的药物组合物，以及它们在治疗由各种靶蛋白介导的病症、疾病和障碍中的用途。