Cardiovascular hazard event prediction and uses thereof

The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for assessing risk of cardiovascular (CV) events within 5 years. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to assess risk of CV events within 5 years. In another aspect, a method is provided for assessing risk of a CV event within 5 years in an individual, where the method comprises detecting, in a biological sample from the individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1. In a further aspect, a method for assessing the risk of CV is provided, where the method comprises detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 2. In a further aspect, a method is provided for assessing the risk of a CV event in an individual generally within 5 years, where