Bovine akabane disease virus vaccine

The invention relates to the technical field of biology, and particularly provides a cattle akabane disease virus vaccine. The protein for preparing the bovine akabane disease virus vaccine comprises G1 protein of bovine akabane disease virus and G2 protein of bovine akabane disease virus, a nucleot...

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Bibliographische Detailangaben
Hauptverfasser: CHENG LANLING, HE SUN, LI JUNHUI, ZHANG WEI, ZHANG SHUQIN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the technical field of biology, and particularly provides a cattle akabane disease virus vaccine. The protein for preparing the bovine akabane disease virus vaccine comprises G1 protein of bovine akabane disease virus and G2 protein of bovine akabane disease virus, a nucleotide sequence for coding the G1 protein is shown as SEQ ID NO.1, and a nucleotide sequence for coding the G2 protein is shown as SEQ ID NO.2. The invention further provides a preparation method of the bovine akabane disease virus vaccine. The protein is suitable for a eukaryotic cell expression system, the process for preparing active ingredients of bovine akabane disease virus vaccines is changed, and meanwhile the cost is reduced. In addition, the protein has broad-spectrum antigenicity, and a good cross protection effect can be achieved. 本发明涉及生物技术领域,具体而言,提供了一种牛赤羽病病毒疫苗。本发明提供制备牛赤羽病病毒疫苗的蛋白,包括牛赤羽病病毒的G1蛋白和牛赤羽病病毒的G2蛋白,其中,编码G1蛋白的核苷酸序列如SEQ ID NO.1所示,编码G2蛋白的核苷酸序列如SEQ IDNO.2所示。该蛋白适用于真核细胞表达系统,改变了牛赤羽病病毒疫苗活性成分制备的工艺,同时降低了成本。并且