Magneto-optical double-field contrast agent as well as preparation method and application thereof

The invention relates to the technical field of material science and biological medicine science and technology, in particular to a magneto-optical double-field contrast agent and a preparation method and application thereof, and the structure of the contrast agent is a superparamagnetic ferroferric...

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Hauptverfasser: GUI WEILING, CHENG CHEN, ZHOU YUXIANG, DONG SIYU, YAO GUIXIANG, KOU HUILING, AN TAIYU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of material science and biological medicine science and technology, in particular to a magneto-optical double-field contrast agent and a preparation method and application thereof, and the structure of the contrast agent is a superparamagnetic ferroferric oxide structure wrapped by hyaluronic acid and mesoporous silica; meanwhile, the mesoporous silica coated superparamagnetic ferriferrous oxide structure is also filled with rare earth elements. On the basis of the magneto-optical double-field contrast agent and controllable and accurate positioning magnetic field contrast, the contrast agent prepared by doping a trace amount of low-toxicity rare earth luminescent material bait further reduces the biotoxicity, realizes optical coherence imaging and magnetic field contrast double-field imaging, enhances the developing effect, and has a wide application prospect. The stenosis degree of the anatomical structure of the coronary artery lumen can be accurately judged, an