Drug-loaded microspheres for targeted inhibition of TNBC cell activity, and preparation method and application thereof

The invention provides a drug-loaded microsphere for targeted inhibition of TNBC cell activity, and a preparation method and application thereof, and relates to the technical field of molecular biology. The microsphere comprises a CD24 aptamer and a carrier, the CD24 aptamer is located on the surface of the carrier, the carrier is a composite microsphere, the composite microsphere comprises a microsphere body and a loading agent, the microsphere body is a PC-coBP microsphere, and the technical problem that the inhibition efficiency of inhibiting TNBC cell activity is low can be mainly solved; the invention also provides a preparation method of the drug-loaded microspheres for targeted inhibition of TNBC cell activity, the preparation method is simple to operate, and batch production of the drug-loaded microspheres for targeted inhibition of TNBC cell activity is facilitated. 本发明提出了一种靶向抑制TNBC细胞活性的载药微球、制备方法及其应用，涉及分子生物学技术领域。该微球包括CD24适体和载体，CD24适体位于载体表面，载体为复合微球，复合微球包括微球本体和负载剂，微球本体为PC-coBP微球，其能够主要解决抑制TNBC细胞活性的抑制效率低