Proteins comprising T-cell receptor constant domain

Provided herein are proteins comprising a T-cell receptor (TCR) constant domain having one or more stable mutations, nucleic acids encoding such proteins, and methods of making and using such proteins. 本文提供了包含具有一个或多个稳定突变的T-细胞受体(TCR)恒定结构域的蛋白、编码此类蛋白的核酸以及制备和使用此类蛋白的方法。...

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Hauptverfasser:	MAGUIRE, JAMES, B, DEMAREST STEPHEN JOHN, FRONING, KEVIN, J, KUHLMAN, BRETT, A
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided herein are proteins comprising a T-cell receptor (TCR) constant domain having one or more stable mutations, nucleic acids encoding such proteins, and methods of making and using such proteins. 本文提供了包含具有一个或多个稳定突变的T-细胞受体(TCR)恒定结构域的蛋白、编码此类蛋白的核酸以及制备和使用此类蛋白的方法。