Monoclonal antibody for resisting flurogesterone acetate and application of monoclonal antibody

The invention discloses a monoclonal antibody for resisting flurogesterone acetate and application of the monoclonal antibody. The monoclonal antibody or antigen binding part contains a VH heavy chain variable region and a VL light chain variable region, and both the VH and the VL consist of an anti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WU DI, ZHAO RONGMAO, WEI SHANPING, WANG JISHENG, LI YAZHOU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a monoclonal antibody for resisting flurogesterone acetate and application of the monoclonal antibody. The monoclonal antibody or antigen binding part contains a VH heavy chain variable region and a VL light chain variable region, and both the VH and the VL consist of an antigenic determinant complementary region and a framework region; the amino acid sequence of the CDR1 of the VH is as shown in the 50th site to the 56th site of SEQ ID No.1; the amino acid sequence of the CDR2 of the VH is as shown in the 76th site to the 92nd site of SEQ ID No.1; the amino acid sequence of the CDR3 of the VH is as shown in the 125th site to the 134 site of SEQ ID No.1; the amino acid sequence of the CDR1 of the VL is as shown in the 60th site to the 76th site of SEQ ID No.2; the amino acid sequence of the CDR2 of the VL is as shown in 92th to 98th sites of SEQ ID No.2; the amino acid sequence of the CDR3 of the VL is as shown in the 131 < th >-138 < th > sites of SEQ ID No. 2. The anti-flugestone ace