Preparation method of isosorbide

A preparation method of isosorbide belongs to the technical field of fine chemical engineering, and comprises molecular sieve cleaning, molecular sieve modification, active substance adsorption and calcination, and isosorbide synthesis. The preparation method of the isosorbide has the advantages that the reaction conditions are mild, the operation is simple, the conversion rate of the reactant sorbitol is high, the selectivity and the yield of the product isosorbide are high, the reaction temperature is 130-230 DEG C, the conversion rate of the sorbitol is 95.32-97.93%, the selectivity of the isosorbide is 75.47-77.43%, and the yield of the isosorbide is 72.89-75.74%. 一种异山梨醇的制备方法，属于精细化工技术领域，包括分子筛清洗、分子筛改性、活性物质吸附和煅烧、异山梨醇的合成。本发明所述异山梨醇的制备方法，反应条件温和，操作简单，反应物山梨醇的转化率高，产物异山梨醇的选择性高、收率高，反应温度为130~230℃，山梨醇的转化率为95.32~97.93%，异山梨醇选择性为75.47~77.43%，异山梨醇收率为72.89~75.74%。