Euconafil oxide as well as preparation method and application thereof

The invention discloses an uconafil oxide as shown in a formula I or pharmaceutically acceptable salt thereof, and a preparation method and application of the compound. The impurity is a degradation impurity of the uconafil hydrochloride, can be used as a reference substance for research of related...

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Bibliographische Detailangaben
Hauptverfasser:	DAI HUASHAN, CAO BING, YIN LIXIAN, ZHAI JIAPING, LIANG HUIXING, LIU XU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The invention discloses an uconafil oxide as shown in a formula I or pharmaceutically acceptable salt thereof, and a preparation method and application of the compound. The impurity is a degradation impurity of the uconafil hydrochloride, can be used as a reference substance for research of related substances, and is used for methodological verification and quality control of the uconafil hydrochloride so as to better control the product quality. 本发明公开了一种式Ⅰ所示的优克那非氧化物或其药学上可接受的盐，以及该化合物的制备方法和用途。该杂质为盐酸优克那非的降解杂质，可用作有关物质研究用对照品，用于盐酸优克那非方法学验证和质量控制，以更好地控制产品质量。