Marker for predicting postoperative distant metastasis risk of colorectal cancer patient and application thereof

The invention provides a marker for predicting the postoperative distant metastasis risk of a colorectal cancer patient and application of the marker. Belongs to the technical field of molecular biomedicine. The group of markers for predicting the postoperative distant metastasis risk of the colorec...

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Bibliographische Detailangaben
Hauptverfasser: YE SHUBIAO, YANG ZIHUAN, LI PEISI, CHEN DONGWEN, LIN ZHENSEN, CHENG YIKAN, LAN PING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a marker for predicting the postoperative distant metastasis risk of a colorectal cancer patient and application of the marker. Belongs to the technical field of molecular biomedicine. The group of markers for predicting the postoperative distant metastasis risk of the colorectal cancer patient consists of an FHL3 protein, a GGA1 protein, an NUDFS7 protein and a TGFBI protein. The biological characteristics of the colorectal cancer patients are reflected through the expression levels of the four protein molecules, the postoperative distant metastasis risk of the colorectal cancer patients can be better predicted, and treatment of the II-stage or III-stage colorectal cancer patients can be better guided. 本发明提供了用于预测结直肠癌患者术后远处转移风险的标志物及其应用。属于分子生物医学技术领域。本发明的一组用于预测结直肠癌患者术后远处转移风险的标志物,由FHL3蛋白、GGA1蛋白、NUDFS7蛋白和TGFBI蛋白组成。本发明通过所述4个蛋白分子的表达水平来反映结直肠癌患者的生物学特性,可以更好的对结直肠癌患者术后远处转移风险进行预测,更好地指导II期或III期结直肠癌患者的治疗。