Synthesis method of methyl thiomethylene ester compound

The invention discloses a synthetic method of a methyl thiomethylene ester compound. According to the method, in the presence of nitrogen and alkali, a carboxylic acid compound reacts with an esterification reagent to form a methyl thiomethylene ester compound; wherein the esterification reagent is brominated dimethyl sulfonium; the alkali is organic alkali or inorganic alkali, and the carboxylic acid compound is p-methoxybenzoic acid, a benzoic acid derivative containing a substituent group on a benzene ring, conjugated carboxylic acid, amino acid and a carboxylic acid compound containing other functional groups or heteroatoms; the raw materials required by the method are simple and easy to obtain, the reaction conditions are simple and convenient, the method is green and energy-saving, the reaction yield is high, the compatibility of substrate functional groups is excellent, and the method has high application value. 本发明公开了一种甲基硫亚甲基酯类化合物的合成方法；该方法在氮气和碱存在的条件下，羧酸化合物和酯化试剂进行反应形成甲基硫亚甲基酯化合物；其中酯化试剂为溴化二甲基锍；碱为有机碱或无机碱，