Method for preparing medical intermediate thiazolo [3, 2-c] pyrimidine-6-nitrile derivative from three components

The invention relates to the field of pharmaceutical chemicals, and particularly discloses a method for preparing a medical intermediate thiazolo [3, 2-c] pyrimidine-6-nitrile derivative from three components, the preparation method comprises the following steps: by taking aromatic aldehyde, malononitrile and 2-amino-4-phenyl-1, 3-thiazole as reaction raw materials, pouring a preset amount of reaction raw materials and a catalyst into a pre-prepared solvent; the method comprises the following steps: adding a thiazol [3, 2-a] pyrimidine-6-nitrile catalyst into a reaction kettle, magnetically stirring at room temperature, and then heating, preserving heat and carrying out suction filtration to obtain the thiazol [3, 2-a] pyrimidine-6-nitrile derivative, aromatic aldehyde, malononitrile and 2-amino-4-phenyl-1, 3-thiazole are used as reaction raw materials, a basic ionic liquid is selected as a catalyst, and the efficiency and the selectivity of catalytic preparation of the thiazolo [3, 2-a] pyrimidine-6-nitrile