Method for producing peptide compound

The present invention addresses the problem of providing a method for efficiently producing a peptide, comprising the following steps (1) and (2): a step (1) in which an N-protected amino acid or an N-protected peptide is mixed with a carboxylic acid halide represented by formula (I); and a step (2) in which the product obtained in step (1) is mixed with a C-protected amino acid or a C-protected peptide. In formula (I), X represents a halogen atom, R1, R2, and R3 each independently represent an optionally substituted aliphatic hydrocarbon group, and the total number of carbon atoms in R1, R2, and R3 is 3 to 40. 本发明的课题在于提供肽的高效的制造方法，提供肽的制造方法，其包括下述工序(1)及(2)：工序(1)，将N-保护氨基酸或N-保护肽、与式(I)表示的羧酸卤化物混合；及工序(2)，将工序(1)中得到的产物、与C-保护氨基酸或C-保护肽混合。式(I)中，X表示卤原子，R1、R2及R3彼此独立地表示可具有取代基的脂肪族烃基，R1、R2及R3中的碳原子的总数为3至40。