CD3 binding antibodies

The present invention relates to novel human CD3 antigen binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also to bispecific antibody molecules capable of activating immune effector cells and their use in the diagnosis and/or treatment of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TRINKLEIN NATHAN, VANSCHOOTEN WIM, PALM, DAVID, HARRIS KATHERINE, ALDRED SHELLEY FORCE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to novel human CD3 antigen binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also to bispecific antibody molecules capable of activating immune effector cells and their use in the diagnosis and/or treatment of various diseases. 本发明涉及新的人CD3抗原结合多肽以及其制备和在各种疾病的治疗和/或诊断中的用途,并且还涉及能够活化免疫效应细胞的双特异性抗体分子以及其在各种疾病的诊断和/或治疗中的用途。