Application of chanterelle polysaccharide in preparation of competitive glucosidase inhibitor
Research tests show that cantharellus cibarius polysaccharide can be used as a competitive glucosidase inhibitor. Cantharellus yunnanensis crude polysaccharide is eluted, separated and purified through distilled water and NaCl to obtain six components, namely CY-0, CY-1, CY-2, CY-4, CY-8 and CY-10,...
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| creator | ZHANG YUZHUO ZENG NIANKAI HAN YUNXIAO ZHANG XU WANG YONG XU CHANG TIAN RUN |
| description | Research tests show that cantharellus cibarius polysaccharide can be used as a competitive glucosidase inhibitor. Cantharellus yunnanensis crude polysaccharide is eluted, separated and purified through distilled water and NaCl to obtain six components, namely CY-0, CY-1, CY-2, CY-4, CY-8 and CY-10, tests show that the CY-2 component belongs to a competitive component for inhibiting activity of glucosidase, and the CY-2 is reversible in inhibition of alpha-glucosidase. The research can provide a theoretical basis for the development and production of related glucosidase inhibitors, and is beneficial to promoting the development of related industries of the glucosidase inhibitors.
本研究试验表明鸡油菌多糖可作为竞争型葡萄糖苷酶抑制剂使用。本发明将云南鸡油菌粗多糖通过蒸馏水和NaCl洗脱分离纯化后得到6个组分，分别为CY-0、CY-1、CY-2、CY-4、CY-8、CY-10，试验表明CY-2组分属于竞争型抑制葡萄糖苷酶活性的组分，且CY-2对α-葡萄糖苷酶抑制为可逆性的。本研究可为相关葡萄糖苷酶抑制剂的研制和生产提供理论依据，有利于推动葡萄糖苷酶抑制剂相关产业的发展。 |
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本研究试验表明鸡油菌多糖可作为竞争型葡萄糖苷酶抑制剂使用。本发明将云南鸡油菌粗多糖通过蒸馏水和NaCl洗脱分离纯化后得到6个组分，分别为CY-0、CY-1、CY-2、CY-4、CY-8、CY-10，试验表明CY-2组分属于竞争型抑制葡萄糖苷酶活性的组分，且CY-2对α-葡萄糖苷酶抑制为可逆性的。本研究可为相关葡萄糖苷酶抑制剂的研制和生产提供理论依据，有利于推动葡萄糖苷酶抑制剂相关产业的发展。</description><language>chi ; eng</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; POLYSACCHARIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220426&DB=EPODOC&CC=CN&NR=114392268A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220426&DB=EPODOC&CC=CN&NR=114392268A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG YUZHUO</creatorcontrib><creatorcontrib>ZENG NIANKAI</creatorcontrib><creatorcontrib>HAN YUNXIAO</creatorcontrib><creatorcontrib>ZHANG XU</creatorcontrib><creatorcontrib>WANG YONG</creatorcontrib><creatorcontrib>XU CHANG</creatorcontrib><creatorcontrib>TIAN RUN</creatorcontrib><title>Application of chanterelle polysaccharide in preparation of competitive glucosidase inhibitor</title><description>Research tests show that cantharellus cibarius polysaccharide can be used as a competitive glucosidase inhibitor. Cantharellus yunnanensis crude polysaccharide is eluted, separated and purified through distilled water and NaCl to obtain six components, namely CY-0, CY-1, CY-2, CY-4, CY-8 and CY-10, tests show that the CY-2 component belongs to a competitive component for inhibiting activity of glucosidase, and the CY-2 is reversible in inhibition of alpha-glucosidase. The research can provide a theoretical basis for the development and production of related glucosidase inhibitors, and is beneficial to promoting the development of related industries of the glucosidase inhibitors.
本研究试验表明鸡油菌多糖可作为竞争型葡萄糖苷酶抑制剂使用。本发明将云南鸡油菌粗多糖通过蒸馏水和NaCl洗脱分离纯化后得到6个组分，分别为CY-0、CY-1、CY-2、CY-4、CY-8、CY-10，试验表明CY-2组分属于竞争型抑制葡萄糖苷酶活性的组分，且CY-2对α-葡萄糖苷酶抑制为可逆性的。本研究可为相关葡萄糖苷酶抑制剂的研制和生产提供理论依据，有利于推动葡萄糖苷酶抑制剂相关产业的发展。</description><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>POLYSACCHARIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwkAMgOFbHER9h_gADm1FdCxFcXJylRKvaRs4L-EuCr69CoKr0w8_39RdatXAHo0lgvTgR4xGiUIgUAnPjP69EncEHEETKaYflpuSsfGDYAh3L5k7zB858pVN0txNegyZFt_O3PKwPzfHFam0lBU9RbK2ORXFutqV5WZbV_-YF4WGPVw</recordid><startdate>20220426</startdate><enddate>20220426</enddate><creator>ZHANG YUZHUO</creator><creator>ZENG NIANKAI</creator><creator>HAN YUNXIAO</creator><creator>ZHANG XU</creator><creator>WANG YONG</creator><creator>XU CHANG</creator><creator>TIAN RUN</creator><scope>EVB</scope></search><sort><creationdate>20220426</creationdate><title>Application of chanterelle polysaccharide in preparation of competitive glucosidase inhibitor</title><author>ZHANG YUZHUO ; ZENG NIANKAI ; HAN YUNXIAO ; ZHANG XU ; WANG YONG ; XU CHANG ; TIAN RUN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN114392268A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>POLYSACCHARIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG YUZHUO</creatorcontrib><creatorcontrib>ZENG NIANKAI</creatorcontrib><creatorcontrib>HAN YUNXIAO</creatorcontrib><creatorcontrib>ZHANG XU</creatorcontrib><creatorcontrib>WANG YONG</creatorcontrib><creatorcontrib>XU CHANG</creatorcontrib><creatorcontrib>TIAN RUN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG YUZHUO</au><au>ZENG NIANKAI</au><au>HAN YUNXIAO</au><au>ZHANG XU</au><au>WANG YONG</au><au>XU CHANG</au><au>TIAN RUN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Application of chanterelle polysaccharide in preparation of competitive glucosidase inhibitor</title><date>2022-04-26</date><risdate>2022</risdate><abstract>Research tests show that cantharellus cibarius polysaccharide can be used as a competitive glucosidase inhibitor. Cantharellus yunnanensis crude polysaccharide is eluted, separated and purified through distilled water and NaCl to obtain six components, namely CY-0, CY-1, CY-2, CY-4, CY-8 and CY-10, tests show that the CY-2 component belongs to a competitive component for inhibiting activity of glucosidase, and the CY-2 is reversible in inhibition of alpha-glucosidase. The research can provide a theoretical basis for the development and production of related glucosidase inhibitors, and is beneficial to promoting the development of related industries of the glucosidase inhibitors.
本研究试验表明鸡油菌多糖可作为竞争型葡萄糖苷酶抑制剂使用。本发明将云南鸡油菌粗多糖通过蒸馏水和NaCl洗脱分离纯化后得到6个组分，分别为CY-0、CY-1、CY-2、CY-4、CY-8、CY-10，试验表明CY-2组分属于竞争型抑制葡萄糖苷酶活性的组分，且CY-2对α-葡萄糖苷酶抑制为可逆性的。本研究可为相关葡萄糖苷酶抑制剂的研制和生产提供理论依据，有利于推动葡萄糖苷酶抑制剂相关产业的发展。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | Application of chanterelle polysaccharide in preparation of competitive glucosidase inhibitor |
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