System and method for automated treatment planning and optimization

Systems and methods for automatically generating and optimizing radiation therapy treatment plans, and systems and methods for automatically generating and optimizing adaptive plans in an adaptive radiation therapy workflow. In one embodiment, an automatic treatment planning system includes: a user interface; and a treatment planning module configured to automatically generate S110 one or more treatment planning candidates based on a weighted combination of a first set of targets derived for clinical data of the first data source and a second set of targets derived for clinical data of a different second data source received via the user interface. 用于自动生成和优化放射疗法治疗计划的系统和方法，以及用于自动生成和优化自适应放射疗法工作流中的自适应计划的系统和方法。在一个实施例中，自动治疗计划系统包括：用户接口；以及治疗计划模块，其被配置为基于经由用户接口接收到的针对第一数据源的临床数据而导出的目标的第一集合和针对不同的第二数据源的临床数据而导出的目标的第二集合的加权组合来自动生成S110一个或多个治疗计划候选。