Method for preparing ursodeoxycholic acid

Described is a chemical-enzymatic process for the preparation of ursodeoxycholic acid (UDCA) starting from deoxycholic acid (DCA), the chemical-enzymatic process comprising the preparation of an enzyme having high 7 [beta]-hydroxylase activity for the conversion of deoxycholic acid (DCA) to bear bil...

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Bibliographische Detailangaben
Hauptverfasser:	RAPACIOLI SILVIA, VERGA ROBERTO, GARDI GIANLUCA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described is a chemical-enzymatic process for the preparation of ursodeoxycholic acid (UDCA) starting from deoxycholic acid (DCA), the chemical-enzymatic process comprising the preparation of an enzyme having high 7 [beta]-hydroxylase activity for the conversion of deoxycholic acid (DCA) to bear bile acid (UCA), the conversion being the first step of the process. 描述了一种用于从脱氧胆酸(DCA)开始制备熊脱氧胆酸(UDCA)的化学-酶促方法，所述化学-酶促方法包括制备具有用于将脱氧胆酸(DCA)转化为熊胆酸(UCA)的高7β-羟化酶活性的酶，所述转化是所述方法的第一步。