Preparation method of carbon-loaded iron-based catalyst and synthesis application of anticancer inhibitor intermediate of carbon-loaded iron-based catalyst

The invention aims to provide a preparation method of a carbon-loaded iron-based catalyst and synthesis application of an anticancer inhibitor intermediate of the carbon-loaded iron-based catalyst, ferric chloride is dissolved in water, activated carbon is added, and the mixture is heated to 60-100...

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Hauptverfasser: YANG TIANBAO, LI CHENGHAN, LU HAO, YIN SHUANGFENG, QIU RENHUA, KANBE NOBUAKI, LI DINGZHONG, ZHANG WENSHENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention aims to provide a preparation method of a carbon-loaded iron-based catalyst and synthesis application of an anticancer inhibitor intermediate of the carbon-loaded iron-based catalyst, ferric chloride is dissolved in water, activated carbon is added, and the mixture is heated to 60-100 DEG C, so that the high-activity monatomic iron catalyst can be obtained. According to the method, the prepared monatomic iron-based carbon-doped material is used as a catalyst, hydrazine hydrate is used as a hydrogen source, and a key intermediate is synthesized at a high yield through reaction in solvents such as methanol, ethanol and isopropanol under mild conditions. The method has the advantages that a high-purity target product can be obtained only through suction filtration and washing, the solvent can be recycled, and the catalyst can be repeatedly used for ten times after being washed, dried and activated by the solvent. The preparation method of the catalyst is simple in process, green, efficient, low in