Compounds and methods for treating or preventing hematologic cancer

The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with a DHODH inhibitor, such as 6-fluoro-2-(2 '-fluoro-[1, 1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid. 本发明包括用DHODH抑制剂如6-氟-2-(2'-氟-[1,1'-联苯]-4-基)-...

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Bibliographische Detailangaben
Hauptverfasser:	SYKES DAVID B, JANSER ANDREAS, SCADDEN DANIEL, MEYER HEIKO, LEWIS TIMOTHY A, STODGETT, DAVID
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with a DHODH inhibitor, such as 6-fluoro-2-(2 '-fluoro-[1, 1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid. 本发明包括用DHODH抑制剂如6-氟-2-(2'-氟-[1,1'-联苯]-4-基)-3-甲基喹啉-4-甲酸治疗跨越一系列遗传亚型的急性髓性白血病患者的方法。