Monoclonal antibody for resisting human immunoglobulin kappa light chain, preparation method thereof, immunodetection reagent and application
The invention belongs to the field of monoclonal antibodies, and particularly relates to an anti-human immunoglobulin kappa light chain monoclonal antibody, a preparation method thereof, an immunodetection reagent and an application of the anti-human immunoglobulin kappa light chain monoclonal antib...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the field of monoclonal antibodies, and particularly relates to an anti-human immunoglobulin kappa light chain monoclonal antibody, a preparation method thereof, an immunodetection reagent and an application of the anti-human immunoglobulin kappa light chain monoclonal antibody. The monoclonal antibody comprises a VHCDR1, a VHCDR2 and a VHCDR3 of which the amino acid sequences are shown as SEQ ID NO: 1-3, and a VLCDR1, a VLCDR2 and a VLCDR3 of which the amino acid sequences are shown as SEQ ID NO: 4-6. The invention provides a diagnostic reagent for evaluating lymphoma or lymph node reactive hyperplasia, the diagnostic reagent can replace an imported reagent, localization of the diagnostic reagent is realized, and the diagnostic cost is greatly reduced. In the aspect of reagent application, compared with an internationally widely used L1C1 monoclonal antibody, the monoclonal antibody for resisting the human immunoglobulin kappa light chain has the advantages that the specificity evalu |
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