Anti-human statin alpha monoclonal antibody, preparation method thereof, immunodetection reagent and application

The invention belongs to the field of monoclonal antibodies, and particularly relates to an anti-human statin alpha (Inhistatin-alpha) monoclonal antibody as well as a preparation method, an immunodetection reagent and application thereof. The monoclonal antibody comprises a VHCDR1, a VHCDR2 and a V...

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Hauptverfasser: ZHAI JINYU, XU PENGCHENG, WANG XIAOYA, LI SANHUA, WANG YUANLI, LI YANJUAN, QI HUA, CHANG QIUSHUANG, QIN ZHIJIE, WU XIAMENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of monoclonal antibodies, and particularly relates to an anti-human statin alpha (Inhistatin-alpha) monoclonal antibody as well as a preparation method, an immunodetection reagent and application thereof. The monoclonal antibody comprises a VHCDR1, a VHCDR2 and a VHCDR3 of which the amino acid sequences are shown as SEQ ID NO: 1-3, and a VLCDR1, a VLCDR2 and a VLCDR3 of which the amino acid sequences are shown as SEQ ID NO: 4-6. The anti-human statin alpha monoclonal antibody provided by the invention can accurately identify Inhibin-alpha protein expressed in paraffin tissue and frozen tissue, and compared with an imported reagent R1, the monoclonal antibody has the advantages of consistent specific evaluation result, low antibody use concentration and stronger dyeing effect, and can be used for immunodetection analysis. The monoclonal antibody has important significance for realizing localization of the monoclonal antibody and reducing reagent cost. 本发明属于单克隆抗体领域,具体涉及一种抗人抑制素