Arterial blood vessel imaging agent and application thereof

The embodiment of the invention provides an application of a molecular probe 11C-A-752274 as an artery blood vessel imaging agent, and the 11C-A-752274 has a structure as shown in a formula 1; the molecular probe 11C-A-752274 provided by the invention can be specifically combined with the alpha7 nic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LIANG YINGKUI, GUO FENG, WANG DAWEI, CHEN XIANGYI, ZOU HANZHUO
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The embodiment of the invention provides an application of a molecular probe 11C-A-752274 as an artery blood vessel imaging agent, and the 11C-A-752274 has a structure as shown in a formula 1; the molecular probe 11C-A-752274 provided by the invention can be specifically combined with the alpha7 nicotinic acetylcholine receptor expressed in the VASPs, and the affinity of the molecular probe 11C-A-752274 with the alpha7 nicotinic acetylcholine receptor expressed in the VASPs is proper, so that accurate recognition of the VASPs is realized, and the molecular probe 11C-A-752274 can be used for an artery blood vessel imaging agent. 本申请实施例提供了分子探针11C-A-752274作为动脉血管显像剂的用途,其中,11C-A-752274具有式1所示的结构;本申请提供的分子探针11C-A-752274,可以与VASPs中表达的α7烟碱型乙酰胆碱受体特异性结合,与VASPs中表达的α7烟碱型乙酰胆碱受体的亲和力适当,从而实现VASPs的准确识别,因此能够用于动脉血管显像剂。