Magnetic bead coating substance, preparation method thereof and detection kit

The invention relates to a magnetic bead coating substance, a preparation method thereof and a detection kit. The preparation method of the magnetic bead coating substance comprises the following steps: preparing cationic bovine serum albumin by adopting polyamine modified bovine serum albumin, and coupling the nano magnetic beads and the active substance through the cationic bovine serum albumin to prepare the magnetic bead coating substance. By adopting the preparation method of the magnetic bead coating substance to prepare the magnetic bead coating substance, the specificity of the magnetic bead coating substance and the immunogenicity of the active substance coated on the magnetic bead can be improved, so that the specificity, the signal-to-noise ratio, the sensitivity and the detection rate of the magnetic bead coating substance during detection are improved. 本发明涉及一种磁珠包被物及其制备方法和检测试剂盒。该磁珠包被物的制备方法包括以下步骤：采用多胺修饰牛血清白蛋白制备阳离子牛血清白蛋白，及将纳米磁珠与活性物质通过阳离子牛血清白蛋白偶联制备磁珠包被物。采用上述磁珠包被物的制备方法制备磁珠包被物，能够提高磁珠包被物的特异性和包被在磁珠上的活性物质