Universal cell backpack polymer system and preparation method thereof

The invention discloses a universal cell backpack polymer system and a preparation method thereof, and belongs to the field of polymer nano biological materials, the cell backpack polymer system comprises: cells and reactive polymer nanoparticles; the reactive polymer nanoparticles include a reactive amide polymer; wherein the reactive polymer nanoparticles are located on the cell surface of the cell. The cell backpack polymer system disclosed by the invention has good cell compatibility, and the cell binding mechanism is mainly hydrogen bonds and/or covalent bonds between the polymer and cell surface molecules without depending on a specific receptor, so that the cell backpack polymer system can reside on the cell surface for a long time; and the preparation method has flexibility and universality, and the backpack function can be customized according to functional proteins and cell types. 本发明公开了一种普适性细胞背包聚合物系统及其制备方法，属于聚合物纳米生物材料领域，该细胞背包聚合物系统包括：细胞和反应性聚合物纳米粒子；反应性聚合物纳米粒子包括反应性酰胺聚合物；其中，反应性聚合物纳米粒子位于细胞的细胞表面上。本发明的细胞背