Ionizable cationic compound and application of compound thereof
The invention discloses an ionizable cationic compound and application of a compound of the ionizable cationic compound, and belongs to the technical field of biological medicine, and the application of the ionizable cationic compound comprises at least one of the following 1)-4): 1) encapsulating a...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an ionizable cationic compound and application of a compound of the ionizable cationic compound, and belongs to the technical field of biological medicine, and the application of the ionizable cationic compound comprises at least one of the following 1)-4): 1) encapsulating a treatment or prevention agent; 2) in-vitro cell transfection of the therapeutic or prophylactic agent; 3) preparing a therapeutic or prophylactic agent in-vivo delivery reagent; and 4) preparing the transfection kit. The compound comprises a therapeutic or prophylactic agent and a carrier for delivering the therapeutic or prophylactic agent, and the carrier is the ionizable cationic compound or the pharmaceutically available salt, solvate or prodrug of the ionizable cationic compound. The compound provided by the invention has relatively high transfection efficiency, good delivery efficiency and relatively low toxicity, can be applied to in-vivo and in-vitro delivery of therapeutic agents or prophylactic agents, e |
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