Synthesis method of 2, 6-diphenyl pyrone compound

The invention discloses a synthesis method of a 2, 6-diphenyl pyrone compound, which comprises the following steps: step 1, methyl benzoate and sodium methoxide are used as raw materials, and react to generate 1, 5-diphenyl-1, 3, 5-triketone, and the molar ratio of methyl benzoate to sodium methoxid...

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Bibliographische Detailangaben
Hauptverfasser: REN YINGGE, GUO SUILIN, ZHANG YANFENG, GUO HONGMEI, ZHUO XINGZHOU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a synthesis method of a 2, 6-diphenyl pyrone compound, which comprises the following steps: step 1, methyl benzoate and sodium methoxide are used as raw materials, and react to generate 1, 5-diphenyl-1, 3, 5-triketone, and the molar ratio of methyl benzoate to sodium methoxide is 1: (2-5); 2, 1, 5-diphenyl-1, 3, 5-triketone is subjected to high-temperature ring removal and closing in the presence of a dehydrating agent, the 2, 6-diphenyl pyrone compound is obtained, and the molar ratio of 1, 5-diphenyl-1, 3, 5-triketone to the dehydrating agent is 1: (1-2). 本发明公开了一种2,6-二苯基吡喃酮化合物的合成方法,包括以下步骤:步骤1:以苯甲酸甲酯和甲醇钠为原料,反应生成1,5-二苯基-1,3,5-三酮,其中苯甲酸甲酯和甲醇钠的摩尔比为1:2~5;步骤2:1,5-二苯基-1,3,5-三酮在脱水剂存在下高温脱关环得到2,6-二苯基吡喃酮类化合物,其中1,5-二苯基-1,3,5-三酮和脱水剂的摩尔比为1:1~2。