Method for synthesizing 2-(2-hydroxy-5-tert-octylphenyl) benzotriazole through continuous flow

The invention belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing 2-(2 '-hydroxy-5'-tert-octylphenyl) benzotriazole through continuous flow, which comprises the following steps: taking a compound shown as a formula I as a raw material,...

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Hauptverfasser: LIU BIN, HU XINLI, XIANG ZHANBO, LI ZHAOLIANG, DOU SHENGHUA, JIAO GUOQING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of organic synthesis, and particularly relates to a method for synthesizing 2-(2 '-hydroxy-5'-tert-octylphenyl) benzotriazole through continuous flow, which comprises the following steps: taking a compound shown as a formula I as a raw material, and carrying out reduction reaction on the compound and H2 in a continuous flow reactor under the action of a catalyst to prepare an ultraviolet light absorber 2-(2 '-hydroxy-5'-tert-octylphenyl) benzotriazole, the yield of the target product reaches 95.0% or above, and the purity reaches 99.0% or above. The invention provides a method for preparing 2-(2 '-hydroxy-5'-tert-octylphenyl) benzotriazole through continuous flow, and the method is green and environment-friendly in process, simple and convenient to operate and good in process safety. 本发明属有机合成技术领域,特别涉及一种连续流合成2-(2'-羟基-5'-特辛基苯基)苯并三唑的方法,以式Ⅰ化合物为原料,在催化剂作用下,在连续流反应器中与H2发生还原反应,制备得到紫外线吸收剂2-(2'-羟基-5'-特辛基苯基)苯并三唑,目标产物收率达95.0%以上,纯度达99.0%以上。本发明提供了一种连续流制备2-(2'-羟基-5'-特辛基苯基)苯并三唑的方法,