Microfluidic chip for rapidly detecting bacterial drug resistance for single cell recognition, preparation and application

The invention relates to a micro-fluidic chip for rapidly detecting bacterial drug resistance for single cell recognition, and preparation and application thereof, and belongs to the field of micro-fluidic and biomedical examination. The chip comprises a medicine injection area, a bacterium injectio...

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Hauptverfasser: SONG KENA, YU ZHANGQING, HUANG LEI, ZU XIANGYANG, CHEN HUIMIN, FU DONGLIAO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a micro-fluidic chip for rapidly detecting bacterial drug resistance for single cell recognition, and preparation and application thereof, and belongs to the field of micro-fluidic and biomedical examination. The chip comprises a medicine injection area, a bacterium injection area and a reaction area, the middle area is the reaction area, 16 channels which are independent of one another are designed on the two sides of the chip respectively, 16 channels are formed by dividing multiple times through a fillet channel structure, the channels on the two sides serve as the medicine injection area and the bacterium injection area respectively according to requirements, and the chip is used for one-bacterium-multiple-medicine or one-bacterium-multiple-medicine-resistance high-throughput detection. The method is matched with imaging devices such as a microscope to count bacteria, draws a bacteria growth curve in a short time, and has the advantages of high flux, high precision, low cost, low