Hydrated acellular skin substitute material and manufacturing method thereof

The invention relates to an acellular skin substitute material in a hydrated state and a manufacturing method thereof. In the present invention, an acellular dermis is obtained by excluding an acellular process using a surfactant and an enzyme, and an acellular skin substitute material imparted with soft characteristics can be produced by treatment in a sodium sulfide solution and immersion in a biogenic polymer solution. 本发明涉及水合态的无细胞化皮肤替代材料及其制造方法。在本发明中，通过排除使用表面活性剂和酶的无细胞工艺来获得无细胞真皮，且可以通过硫化钠溶液中的处理和生物源性高分子溶液中的浸渍来制造赋予了柔软的特性的无细胞化皮肤替代材料。