2, 6-dihydroxy benzoic acid dexhandryl ester compound and pharmaceutical application thereof

The invention relates to a 2, 6-dihydroxy benzoic acid dexhanhol ester compound, the structure of which accords with a general formula (I) in which R is-H,-OH,-NR1R2, or-CONR3R4. R1 and R2 are-H, alkyl with 1 to 6 carbon atoms, or-COR5; r < 3 >, R < 4 > and R < 5 > are-H and alkyl...

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Hauptverfasser: LI FEI, CHEN QIAN, LI LUNJIA, XU NAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a 2, 6-dihydroxy benzoic acid dexhanhol ester compound, the structure of which accords with a general formula (I) in which R is-H,-OH,-NR1R2, or-CONR3R4. R1 and R2 are-H, alkyl with 1 to 6 carbon atoms, or-COR5; r < 3 >, R < 4 > and R < 5 > are-H and alkyl with 1-3 carbon atoms. The medicine has good effects of reducing stroke injury and easing pain, and can be used for preparing medicines for treating stroke injury and neuropathic pain. 2,6-二羟基苯甲酸右崁醇酯类化合物,结构符合通式(I)其中:R=-H,-OH,-NR1R2,或-CONR3R4。R1,R2=-H,1-6个碳原子的烷基,或-COR5;R3,R4,R5=-H,1-3个碳原子的烷基。该类药物具有良好的减少卒中损伤、镇痛的作用,可用于制备治疗脑卒中损伤、神经病理性疼痛的药物。