Application of SiO2 in preparation of anti-radiation medicine or medicine for treating ionizing radiation injury

The invention relates to the field of biological medicines, in particular to application of SiO2 in preparation of anti-radiation medicines or medicines for treating ionizing radiation injury. According to the invention, the new application of SiO2 in preparation of anti-radiation drugs or drugs for treating ionizing radiation injury is discovered and confirmed for the first time, and the SiO2 has a prominent effect in the aspect of relieving radiation injury of bone marrow, spleen and intestinal tract; meanwhile, the occurrence mechanism of the application is preliminarily explored, that is, SiO2 plays a radiation protection role mainly through a NOD2/NF-kappa B pathway, and a new prevention and treatment strategy is provided for radiation protection. 本发明涉及生物医药领域，具体涉及SiO2在制备抗辐射药物或治疗电离辐射损伤药物中的用途。本发明首次发现并证实了SiO2在制备抗辐射药物或治疗电离辐射损伤药物中的新用途，且在缓解骨髓、脾及肠道的辐射损伤方面具有突出效果；同时初步探究了该用途的发生机制，即SiO2主要通过NOD2/NF-κB通路发挥其辐射防护作用，为辐射防护提供了新的防治策略。