Method for rapidly detecting caine local anesthetics added in cosmetics

The invention discloses a method for rapidly detecting caine local anesthetics added in cosmetics, and belongs to the technical field of medicine detection. The method comprises the following steps: mixing a to-be-detected cosmetic with an organic extraction reagent and a protein precipitant to obta...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG ZAIPING, FANG FANG, CAO LING, FENG YOULONG, ZHANG MIAOMIAO, XIA JINGZHU, GONG XU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a method for rapidly detecting caine local anesthetics added in cosmetics, and belongs to the technical field of medicine detection. The method comprises the following steps: mixing a to-be-detected cosmetic with an organic extraction reagent and a protein precipitant to obtain a protein precipitate and a supernatant, mixing the supernatant with nano sol and an enhancing aid, and testing the surface enhanced Raman spectrum of the mixture; the nano sol comprises metal nano sol, and the reinforcing auxiliary agent comprises haloid. Whether the caine local anesthetics are added into the cosmetics or not can be rapidly detected on site, and therefore the detection precision and the detection efficiency are improved at the same time. 本发明公开了一种快速检测化妆品中添加卡因类局部麻醉药的方法,属于药品检测技术领域。它包括取待测化妆品与有机提取试剂和蛋白沉淀剂混合获得蛋白质沉淀和上清液,将上清液与纳米溶胶和增强助剂混合后测试混合物的表面增强拉曼光谱;所述纳米溶胶包括金属纳米溶胶,所述增强助剂包括卤素盐。本发明能实现现场快速检测化妆品中是否添加卡因类局麻药,从而同时提升检测精度和检测效率。