Liposome formulations of vilanterol triphenylacetate

The present invention relates to liposomal formulations comprising a lipid component encapsulating vilanterol triphenylacetate, and methods of administering the liposomal formulations by aerosolizing the liposomal formulations in an inhaler. The liposome formulation comprises vilanterol or a salt thereof, and a lipid component comprising a pharmaceutical lipid and/or sterol. The mass ratio of drug to lipid is in the range of about 1: 20 to about 1: 100. Furthermore, the present invention relates to the use of liposome formulations for the prevention or treatment of respiratory diseases, such as chronic obstructive pulmonary disease and/or asthma. 本发明涉及包含包裹三苯乙酸维兰特罗的脂质成分的脂质体制剂，以及通过在吸入器中雾化脂质体制剂来施用脂质体制剂的方法。脂质体制剂包含维兰特罗或其盐，以及包含药物脂质和/或甾醇的脂质成分。药物与脂质的质量比在约1:20至约1:100的范围内。此外，本发明涉及脂质体制剂用于预防或治疗呼吸系统疾病如慢性阻塞性肺病和/或哮喘的用途。