Traceable and anti-apoptosis neural stem cell as well as preparation method and application thereof

The invention discloses a traceable and anti-apoptosis neural stem cell as well as a preparation method and application thereof. The neural stem cell overexpresses Bcl-2 protein and FTH protein. The preparation method comprises the following steps: 1) providing neural stem cells; 2) constructing a lentivirus expression vector; 3) packaging the lentivirus; and 4) infecting the neural stem cell by using the recombinant lentivirus to obtain the neural stem cell connected with a promoter Netin, an mCherry reporter gene, an rFTH1 gene and an rBcl2 gene. The traceable and anti-apoptosis engineered neural stem cell is obtained through joint modification of FTH1 and Bcl2 double genes, has the characteristics of anti-apoptosis ability and MRI visualization at the same time, can be used for treating cerebral infarction, can improve the survival rate of transplanted cells, inhibits cell apoptosis caused by a pathological environment, and can be used for treating cerebral infarction. And the conditions of positioning, di