CD22 antibody and application thereof

The invention provides an antibody capable of specifically recognizing CD22 or an antigen binding fragment thereof. The antibody contains at least one of the following CDR sequences or amino acid sequences with at least 95% identity with the CDR sequences: heavy chain variable region CDR sequences:...

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Bibliographische Detailangaben
Hauptverfasser:	WANG BAOLEI, WANG XIANJIN, GONG CHUNXI, PENG LIANG, DU XIAOLONG, LUO YING, YE LIJUN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides an antibody capable of specifically recognizing CD22 or an antigen binding fragment thereof. The antibody contains at least one of the following CDR sequences or amino acid sequences with at least 95% identity with the CDR sequences: heavy chain variable region CDR sequences: SEQ ID NO: 1-15, and light chain variable region CDR sequences: SEQ IN NO: 16-30. The antibody can specifically recognize CD22, and has high affinity with CD22. 本发明提出了一种能够特异性识别CD22的抗体或其抗原结合片段。该抗体含有选自下列至少之一的CDR序列或与其具有至少95％同一性的氨基酸序列：重链可变区CDR序列：SEQ ID NO:1～15，轻链可变区CDR序列：SEQ IN NO:16～30。该抗体能够特异性识别CD22，与CD22的亲和力高。