Composition for preventing or treating respiratory tract inflammation and use thereof

The present invention relates to a composition and a health functional food using a mixed herbal mixture for preventing and treating inflammatory diseases of the respiratory tract. The combined extract of the present invention exhibits a more effective inhibitory effect on inflammatory diseases of t...

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Hauptverfasser: KIM HYO-GEUN, GUO XIAOMIN, KYUNG JONG-SU, IN GYO, LEE MOON-YONG, SHIN HAN-JAE, ZHANG JINGHUA, HAN, CHANG-KYUN, KIM SEUNG-HYUNG, KIM YOUNG-SHIN, KIM JONG-HAN, MIN HYE-JEONG, KIM SUNG-WON
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a composition and a health functional food using a mixed herbal mixture for preventing and treating inflammatory diseases of the respiratory tract. The combined extract of the present invention exhibits a more effective inhibitory effect on inflammatory diseases of the respiratory tract than the individual herbal extracts: for example, determination of the number of cells of BAL (bronchoalveolar lavage fluid) (Experimental Embodiments 1); determining the ratio of CD11b < + >/Gr-1 < + > in leukocytes in a BAL solution (experiment embodiment 2); determining the RNA expression level of inflammatory cytokines in lung tissue (experimental embodiment 3); determining the RNA expression level of an inflammatory cytokine in BALF (Experimental Embodiments 4); lung histology (experiment embodiment 5); and clinical tests (experimental embodiment 7) and the like are simple. Therefore, the herbal extract according to the present invention can be effectively used in a pharmaceutical composit