Cyclic beta-1,2-glucan and curcumin inclusion compound and preparation method thereof

The invention discloses a cyclic beta-1,2-glucan and curcumin inclusion compound and a preparation method thereof, and belongs to the technical field of biology. The invention provides preparation and characterization of cyclic beta-1, 2-glucan by a fermentation method as well as a preparation metho...

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Bibliographische Detailangaben
Hauptverfasser: WU CHUANCHAO, ZHANG HONGTAO, JIANG YUN, ZHAN XIAOBEI, ZHU LI, WU JIANRONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a cyclic beta-1,2-glucan and curcumin inclusion compound and a preparation method thereof, and belongs to the technical field of biology. The invention provides preparation and characterization of cyclic beta-1, 2-glucan by a fermentation method as well as a preparation method and structural analysis of curcumin, and belongs to the technical field of biology. According to the invention, fermentation synthesis (two-stage pH fermentation) is carried out in a 7-L fermentation tank, and the yield reaches 2.79 g/L. Pure neutral oligosaccharide obtained through purification methods such as ethanol fractional alcohol precipitation, SPE solid-phase extraction, DEAE-Sepharose FF ion exchange column chromatography and the like is identified as the cyclobeta-1, 2-glucan which is composed of glucose monomers, has the polymerization degree range of 17-23 and mainly has the polymerization degree of 19. The inclusion compound is successfully formed by the ring beta-1,2-glucan and the curcumin, so tha