Intermediates of pregnane saponin P57 and derivatives thereof, preparation method and application of intermediates, and pregnane saponin P57 derivatives

The invention relates to intermediates, as shown in a formula I, for pregnane saponin P57 and derivatives thereof, a preparation method and application of the intermediates, and the pregnane saponin P57 derivatives. According to the method, synthesis of P57 and derivatives thereof is realized by ado...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YU BIAO, CHEN XIAOPING, WANG RUINA, DANG YONGJUN, XU PENG, LI ZENGXIA, MA YUYONG, PEI CHENGFENG, ZHANG XIAHENG, JIANG WEI, LIU CHAO, MA JUNJUN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to intermediates, as shown in a formula I, for pregnane saponin P57 and derivatives thereof, a preparation method and application of the intermediates, and the pregnane saponin P57 derivatives. According to the method, synthesis of P57 and derivatives thereof is realized by adopting a convergent synthesis strategy, a synthesis route is short, yield is high, and the method is suitable for industrial production. Each substituent in the formula I is as defined in the specification. 本发明涉及式I所示的用于孕甾皂苷P57及其衍生物的中间体、制备方法和用途、及孕甾皂苷P57衍生物。该方法采用汇聚式合成策略实现了P57及其衍生物的合成,合成路线短,收率高,适合工业化生产。式I中的各取代基的定义与权利要求书中的定义相同。