Nitrogen-containing compound as well as preparation method and application thereof

The invention discloses a nitrogen-containing compound as well as a preparation method and application thereof. The invention provides a nitrogen-containing compound represented by a formula I or a salt thereof. The compound is beneficial to the quality control of nalbuphine hydrochloride, and the medication safety is improved. Meanwhile, the nitrogen-containing compound represented by the formula I can be prepared through three-step reaction by taking thebaine as a raw material, and the preparation method is relatively efficient. 本发明公开了一种含氮化合物、其制备方法及应用。本发明提供了一种如式I所示的含氮化合物或其盐。该化合物有助于盐酸纳布啡的质量控制，提升用药安全性。同时，以蒂巴因为原料，经三步反应即可制得如式I所示的含氮化合物，该制备方法较为高效。