Degradable drug-loaded film capable of treating systemic osteoporosis and preparation process of degradable drug-loaded film
The invention discloses a degradable drug-loaded film capable of treating systemic osteoporosis and a preparation process thereof. The film consists of an inner layer and an outer layer, drug-loaded microspheres and drug-loaded electrostatic spinning fibers are combined to form an inner layer struct...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a degradable drug-loaded film capable of treating systemic osteoporosis and a preparation process thereof. The film consists of an inner layer and an outer layer, drug-loaded microspheres and drug-loaded electrostatic spinning fibers are combined to form an inner layer structure, the fibers form an inner layer continuous phase, and the microspheres are evenly distributed on the inner layer in a dispersed phase mode; and the outer layer is independently composed of drug-loaded electrostatic spinning fibers. After being implanted through minimally invasive surgery, the degradable drug-loaded film can degrade sustained-release drugs in a programmed mode, focus in-situ drug delivery and systemic drug delivery are achieved, and the drug utilization rate is high. The process is simple, the material can be completely biodegraded, and the application prospect in the aspect of treating systemic osteoporosis is wide.
本发明公开了一种可治疗全身骨质疏松的可降解载药薄膜及其制备工艺。薄膜由内层和外层构成:载药微球与载药静电纺丝纤维相结合组成内层结构,其中纤维组成内层连续相,微 |
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