Fluoketamine artificial hapten, artificial antigen and preparation method and application thereof

The invention belongs to the technical field of biochemical engineering, and particularly relates to a fluoketamine artificial hapten, an artificial antigen and a preparation method and application thereof. The fluoketamine artificial hapten maximally retains the characteristic structure of the fluoketamine, and has an active group capable of being coupled with carrier protein after chemical modification so that the fluoketamine artificial antigen can be obtained; the further prepared fluoketamine artificial antigen can be used for immunizing to obtain an anti-fluoketamine antibody with high affinity, high sensitivity and strong specificity; the antigen and the antibody can be used for an immunochromatography technology, have the advantages of high sensitivity, strong specificity, easiness in operation, economy, rapidness and the like, and can be used for preliminary screening of the abuse of the fluoketamine. 本发明属于生物化工技术领域，具体涉及一种氟胺酮人工半抗原、人工抗原及其制备方法和应用。本发明的氟胺酮人工半抗原最大程度地保留了氟胺酮的特征结构，且经过化学修饰具有可以与载体蛋白发生偶联的活性基团，可获