Preparation method of anti-helicobacter pylori egg yolk antibody embedded gel particles
The invention discloses a preparation method of anti-helicobacter pylori egg yolk antibody embedded gel particles. The preparation method comprises the following steps of: mixing an egg yolk antibody IgY with a preservative and the like, and carrying out an emulsion reaction to obtain an egg yolk an...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a preparation method of anti-helicobacter pylori egg yolk antibody embedded gel particles. The preparation method comprises the following steps of: mixing an egg yolk antibody IgY with a preservative and the like, and carrying out an emulsion reaction to obtain an egg yolk antibody emulsion; taking gelatin and Arabic gum as a wall material, taking the egg yolk antibody emulsion as a core material, adding the Arabic gum solution and gelatin, adjusting the pH value by using hydrochloric acid, performing stirring to agglomerate the materials into microcapsules, uniformly mixing the microcapsules with a sodium alginate solution to form a mixed solution, slowly dropwise adding the mixed solution into a calcium chloride solution, and performing washing and airing to obtain the anti-helicobacter pylori egg yolk antibody embedded gel particles. The gel bead particles are high in embedding rate, can improve the titer of the antibody and can reduce the activity loss rate of specific immune globu |
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