METHOD FOR PREPARING BIOCOMPATIBLE POLYMER-BASED APIXABAN-LOADED MICROSPHERES

The present invention relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres. More specifically, the present invention relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres, comprising: i) adding a fatty acid or triglyceride to a dispersed phase; and ii) preparing microspheres using a microfluidic method. The method for preparing biocompatible polymer-based Apixaban-loaded microspheres of the present invention can be effectively used in the preparation of microspheres in which Apixaban is stably encapsulated in high contents. 本发明涉及制备基于生物相容性聚合物的负载阿哌沙班的微球的方法。更具体地，本发明涉及制备基于生物相容性聚合物的负载阿哌沙班的微球的方法，其包括：i)将脂肪酸或甘油三酯加入分散相；以及ii)使用微流控法制备微球。本发明的用于制备基于生物相容性聚合物的负载阿哌沙班的微球的方法能够有效地用于制备其中稳定包封高含量的阿哌沙班的微球。