Polypeptide FFDP and application thereof in oocyte in-vitro culture

The invention discloses a polypeptide FFDP and application thereof in oocyte in-vitro culture. The amino acid sequence of the polypeptide FFDP is as shown in SEQ ID NO. 1. Experiments find that the polypeptide FFDP can be applied to PCOS disease affected oocyte development, and especially applied to...

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Bibliographische Detailangaben
Hauptverfasser: LING ZHONGHUI, HOU XIAOJING, SHEN RONG, GUO YAPING, JI CHENBO, ZHANG PINGPING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a polypeptide FFDP and application thereof in oocyte in-vitro culture. The amino acid sequence of the polypeptide FFDP is as shown in SEQ ID NO. 1. Experiments find that the polypeptide FFDP can be applied to PCOS disease affected oocyte development, and especially applied to the aspect of PCOS oocyte in-vitro maturation culture, or applied to the aspect of improving the meiosis defect during oocyte in-vitro maturation culture. 本发明公开了一种多肽FFDP及其在卵母细胞体外培养的应用,该多肽FFDP的氨基酸序列如SEQ ID NO.1所示。实验发现,该多肽FFDP可以应用在PCOS疾病影响卵母细胞发育中,特别是应用在PCOS卵母细胞体外成熟培养方面,或者应用在改善卵母细胞体外成熟培养时的减数分裂缺陷方面。