Traditional Chinese medicine composition for treating postmenopausal osteoporosis

The invention discloses a traditional Chinese medicine composition for treating postmenopausal osteoporosis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight of 20-40 parts of semen cuscutae, 5-15 parts of herba epimedii, 10-20 parts of fru...

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Hauptverfasser: TAN ZHANGKUI, ZHOU GUANGWEN, XUE YAOJUN, XIANG NAN, XIONG MENGXIN, CHE XILONG, ZHU WEI, LI JIA, ZHOU YANA, ZHANG YAN, LI ZHANGQING, HUANG SHIYI, ZHANG LIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a traditional Chinese medicine composition for treating postmenopausal osteoporosis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight of 20-40 parts of semen cuscutae, 5-15 parts of herba epimedii, 10-20 parts of fructus psoraleae, 12-18 parts of fructus trichosanthis, 9-15 parts of red yeast rice and 15-25 parts of fructus crataegi. According to the traditional Chinese medicine composition, osteogenic/adipogenic differentiation of the BMSCs can be regulated and controlled; bone reconstruction balance can be improved; lipid metabolism disorder can be regulated; and AMPK/mTOR/ULK1 signal channels are used for activating autophagy, so that BMSCs osteogenesis is promoted, adipogenesis is inhibited, OC activity is reduced, bone reconstruction balance is recovered, lipid disorder is improved, body quality is improved, bone/lipid metabolism balance is recovered, and the treatment effect of PMOP is exerted. 本发明公开了一种用于治疗绝经后骨质疏松症的中药组合物