Core-coated tablet for treating hypercholesteremia

The invention discloses a core-coated tablet for treating hypercholesteremia and a preparation method thereof. The core-coated tablet is prepared by pressing an inner-layer core and outer-layer particles by a core-coated tablet press, the core-coated tablet contains effective components of ezetimibe and atorvastatin calcium, the inner-layer core is prepared by tabletting and coating atorvastatin calcium particles, and the outer-layer particles are prepared from ezetimibe, a filling agent, a disintegrating agent, an adhesive, a solubilizer and a lubricating agent. The core-coated tablet not only can solve the problem of convenient taking, but also can effectively avoid the interaction of the two main components and maintain the stability of the product. 本发明公开了一种治疗高胆固醇血症的包芯片及其制备方法，该包芯片由内层芯片和外层颗粒用包芯压片机压制而成，该包芯片含有的有效成分为依折麦布和阿托伐他汀钙，内层芯片由阿托伐他汀钙颗粒经压片和包衣制成，外层颗粒由依折麦布和填充剂、崩解剂、粘合剂、增溶剂、润滑剂制成。该包芯片既可以解决服用方便的问题，又可以有效地避免两种主成分发生相互作用，保持产品的稳定性。