INHIBITORS OF METALLO-BETA-LACTAMASES

The present invention relates to novel compounds that act as inhibitors of metallo-beta-lactamases (MBL). The present invention also relates to pharmaceutical compositions comprising such MBL inhibitors, and uses thereof in the treatment of bacterial infections. More generally, the present invention...

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Bibliographische Detailangaben
Hauptverfasser:	LEGRU ALICE, HERNANDEZ JEAN-FRANCOIS, SEVAILLE LAURENT, GAVARA LAURENT, DOCQUIER JEAN-DENIS
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel compounds that act as inhibitors of metallo-beta-lactamases (MBL). The present invention also relates to pharmaceutical compositions comprising such MBL inhibitors, and uses thereof in the treatment of bacterial infections. More generally, the present invention finds applications in any field where bacteria producing MBL must be removed. 本发明涉及用作金属β内酰胺酶(MBL)抑制剂的新化合物。本发明还涉及包含此类MBL抑制剂的药物组合物，及其在治疗细菌感染中的用途。更一般地，本发明在任何必须除去产生MBL的细菌的领域中找到应用。