Anti-cancer composition containing CDK4/6 inhibitor and application of anti-cancer composition

The invention discloses an anti-cancer composition containing a CDK4/6 inhibitor and application of the anti-cancer composition. The anti-cancer composition is composed of the CDK4/6 inhibitor and an STAT3 inhibitor. By adopting the composition, the CDK4/6 inhibitor and the STAT3 inhibitor can gener...

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Hauptverfasser:	CHENG JIAYUN, ZHOU FENG, LYU SHUOSHUO, XIE MENGYAO, ZHAO CHENGGUANG, SHEN YILI, YANG LEHE, HUANG XIAOYING, ZHENG DANDAN, WANG LIANGXING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses an anti-cancer composition containing a CDK4/6 inhibitor and application of the anti-cancer composition. The anti-cancer composition is composed of the CDK4/6 inhibitor and an STAT3 inhibitor. By adopting the composition, the CDK4/6 inhibitor and the STAT3 inhibitor can generate a synergistic effect, so that the drug resistance to a targeting inhibitor is overcome, the clinical curative effect is improved, and a new window is opened for precise treatment of tumors. 本发明公开了一种含CDK4/6抑制剂抗癌组合物及其应用，该抗癌组合物由CDK4/6抑制剂和STAT3抑制剂组成，采用本发明的组合物，两者可产生协同作用，从而克服靶向抑制剂的耐药并提高临床疗效，为肿瘤精准治疗开启新窗口。