MANUFACTURING METHODS FOR PRODUCING ANTI-TNF ANTIBODY COMPOSITIONS

The present invention relates to methods of manufacture for producing anti-TNF antibodies, e.g., the anti-TNF antibody a recombinant anti-TNF antibody having a heavy chain (HC) comprising amino acid sequence SEQ ID NO:36 and a light chain (LC) comprising amino acid sequence SEQ ID NO:37 and composit...

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Bibliographische Detailangaben
Hauptverfasser: SMITH KEVIN D, GANGULY SUBINAY, NEDVED MICHAEL, GROENEVELD MAARTEN, BARNTHOUSE KRISTOPHER, LOPEZ JR
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to methods of manufacture for producing anti-TNF antibodies, e.g., the anti-TNF antibody a recombinant anti-TNF antibody having a heavy chain (HC) comprising amino acid sequence SEQ ID NO:36 and a light chain (LC) comprising amino acid sequence SEQ ID NO:37 and compositions comprising the recombinant anti-TNF antibody. 本发明涉及用于产生抗TNF抗体例如该抗TNF抗体是具有包含氨基酸序列SEQ ID NO:36的重链(HC)和包含氨基酸序列SEQ ID NO:37的轻链(LC)的重组抗TNF抗体的制造方法以及包含该重组抗TNF抗体的组合物。